Immunosenescence (age-related decline in immune response) can lower influenza vaccine effectiveness in adults 65 years and older.^1,2

People aged 65 years and older, experience worse outcomes in response to influenza infection compared to healthy younger adults.²

As a result of influenza infection, people aged 65 years and older are more susceptible to hospitalisations and increased severity of infection often due to comorbidities compared to healthy younger adults. These factors can cause a decreased quality of life and an increased rate of mortality.^3,4